Small Animal Look-Locker Inversion Recovery (SALLI) for Simultaneous Generation of Cardiac T1 Maps and Cine and Inversion Recovery–prepared Images at High Heart Rates: Initial Experience
نویسندگان
چکیده
منابع مشابه
Small animal look-locker inversion recovery (SALLI)
Introduction and purpose Cardiac T1 mapping allows for quantitative analysis of myocardial tissue properties. Pulse sequences for human applications are not suitable for in-vivo studies in small animals.The aim of this study was to develop a single magnetic resonance imaging (MRI) approach for comprehensive assessment of cardiac function and tissue properties in small animals with high heart ra...
متن کاملSimultaneous T1 mapping, cine imaging, and IR-prepared imaging of the rat heart using Small Animal Look-Locker Inversion recovery (SALLI)
Background: T1 mapping of the heart in rodents is challenging due to high heart rates, preventing the use of non-segmented MRI techniques that have been developed for human studies. We propose a novel acquisition and reconstruction scheme generating cardiac T1 maps, cine images and inversion recovery (IR)-prepared images at the same time. Methods: Small Animal Look-Locker Inversion recovery (SA...
متن کاملValidation of Small-Animal Look-Locker Inversion Recovery (SALLI) Cine versus Cine MR in assessment of left ventricular function
Background Small-Animal Look-Locker Inversion Recovery (SALLI) is a novel imaging method that generates simultaneously cardiac T1 maps, cine MR and inversion recovery-prepared images for high heart rates. T1 mapping by SALLI has been tested and compared with histology, however the assessment of left ventricular (LV) function has not yet been validated. Our aim was to compare the measurement of ...
متن کاملAssessment of Diffuse Myocardial Fibrosis in Rats Using Small Animal Look-Locker Inversion Recovery (SALLI) T1 Mapping
Background It has been shown that the concentration of gadopentetate dimeglumine (GdDTPA) in myocardium and blood can be assessed from T1 measurements, and be used to calculate the extracellular volume (ECV) of the myocardium. We hypothesized that diffuse myocardial fibrosis in a small animal model could be quantitatively assessed by measuring myocardial ECV using small animal Look-Locker inver...
متن کاملAssessment of cardiac function and myocardial morphology using small animal Look-Locker inversion recovery (SALLI) MRI in rats.
Small animal magnetic resonance imaging is an important tool to study cardiac function and changes in myocardial tissue. The high heart rates of small animals (200 to 600 beats/min) have previously limited the role of CMR imaging. Small animal Look-Locker inversion recovery (SALLI) is a T1 mapping sequence for small animals to overcome this problem. T1 maps provide quantitative information abou...
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ژورنال
عنوان ژورنال: Radiology
سال: 2011
ISSN: 0033-8419,1527-1315
DOI: 10.1148/radiol.11101943